Fig. 1 · Structure
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GKA-71
Glucokinase Activtor
GKA-71 is an orally active glucokinase activator that enhances glucose phosphorylation, leading to increased insulin secretion. This compound exhibits islet protective effects, making it a potential therapeutic candidate for managing type 2 diabetes. Its ability to modulate glucose homeostasis supports its application in diabetes research and metabolic studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 863504-35-2 |
| Applications | Glucokinase Activtor |
| Formula | C21H23N3O6S2 |
| Molecular Weight | 477.55 |
| SMILES | O=C(C1=CC(OC2=CC=C(C=C2)S(=O)(C)=O)=CC(O[C@H](COC)C)=C1)NC3=NC(C)=NS3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.