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Glaucarubin

Amœbicide

Glaucarubin is a bitter lactone derived from Simaruba glauca, primarily functioning as an amœbicide. It demonstrates significant biological activity in the treatment of amebiasis and is valuable for research applications targeting amoebic infections. With a high level of tolerance, Glaucarubin exhibits LD50 values of 1,600 mg/kg in mice and 6,400 mg/kg in rats, making it a viable candidate for further preclinical studies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1448-23-3
Applications	Amœbicide
Formula	C₂₅H₃₆O₁₀
Molecular Weight	496.55
SMILES	C[C@@]12[C@]3([H])[C@]45[C@@]([C@H]([C@H]([C@@]3(OC5)O)O)C)([H])[C@H](C(O[C@]4([H])C[C@@]1([H])C(C)=C[C@@H]([C@H]2O)O)=O)OC([C@@](C)(O)CC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.