Fig. 1 · Structure

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GlcN-6-P Synthase-IN-1

GlcN-6-P Synthase Inhibitor

GlcN-6-P Synthase-IN-1 is a selective inhibitor of glucosamine-6-phosphate synthase, exhibiting an IC50 of 3.47 μM. This compound demonstrates significant antimicrobial activity and shows effective central nervous system penetration. Additionally, GlcN-6-P Synthase-IN-1 is capable of inhibiting the cytochrome P450 isoform CYP3A4, making it a valuable tool for research in microbiology and pharmacology.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2415311-87-2
Applications GlcN-6-P Synthase Inhibitor
Formula C20H21N7S
Molecular Weight 391.49
SMILES
N=C(N/N=C(C)/C1=C(C)N=C(N/N=C/C2=CC=C(C3=CC=CC=C3)C=C2)S1)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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