Fig. 1 · Structure
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Glibenclamide potassium
Glibenclamide potassium, a potassium salt of Glibenclamide, functions primarily as a sulfonylurea class antidiabetic agent. It enhances insulin secretion from pancreatic beta cells, making it effective in lowering blood glucose levels in type 2 diabetes management. This compound is available in both anhydrous and hydrated forms, with increased solubility compared to unmodified Glibenclamide, thereby facilitating its use in various pharmaceutical and biochemical research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 52169-36-5 |
| Formula | C23H27ClKN3O5S |
| Molecular Weight | 532.09 |
| Synonyms | Glyburide potassium |
| SMILES | O=C([N-]CCC1=CC=C(S(=O)(NC(NC2CCCCC2)=O)=O)C=C1)C3=CC(Cl)=CC=C3OC.[K+] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.