Fig. 1 · Structure
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Glibornuride
KATP Blocker
Glibornuride is an ATP-sensitive potassium (KATP) channel blocker, exhibiting a pKi of 5.75. This compound demonstrates significant antidiabetic activity by influencing insulin secretion through its effect on pancreatic β-cells. It is primarily utilized in research focused on diabetes and metabolic disorders, providing insights into KATP channel modulation and its role in glucose homeostasis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Blocker |
| CAS Number | 26944-48-9 |
| Applications | KATP Blocker |
| Formula | C18H26N2O4S |
| Molecular Weight | 366.48 |
| SMILES | O=S(C1=CC=C(C)C=C1)(NC(N[C@H]2[C@@](C3(C)C)([H])CC[C@@]3(C)[C@H]2O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.