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GLP-1 receptor agonist 18

Catalog No.: A60662
GLP-1 Receptor Agonist
GLP-1 Receptor Agonist 18 is a potent GLP-1 receptor agonist with an EC50 of 0.22 nM. This compound demonstrates significant biological activity by lowering blood glucose levels and promoting weight loss, making it valuable for diabetes research. Its efficacy in modulating GLP-1 receptor signaling positions it as a useful tool for investigating therapeutic strategies in metabolic disorders.
GLP-1 receptor agonist 18 3112736-36-1 GLP-1 Receptor Agonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGLP-1 Receptor Agonist 18 is a potent GLP-1 receptor agonist with an EC50 of 0.22 nM. This compound demonstrates significant biological activity by lowering blood glucose levels and promoting weight loss, making it valuable for diabetes research. Its efficacy in modulating GLP-1 receptor signaling positions it as a useful tool for investigating therapeutic strategies in metabolic disorders.
Product Information
Catalog NumA60662
FormulaC50H52F2N10O5
Molecular Weight911.01
CAS Number3112736-36-1
SMILES[H][C@]1(CC(C)(C)OCC1)C2=CC=C(N([C@]3(C[C@@H]3C)C4=NOC(N4)=O)C(C(N5[C@@H](C)C6=C(N7CCN(C8=CC=C(N(C9CC9)N=C%10)C%10=C8F)C7=O)N(C%11=CC(C)=C(F)C(C)=C%11)N=C6CC5)=O)=C%12)C%12=C2
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GPCR/G Protein > GLP-1 receptors