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GLP-1R agonist 14

GLP-1 Receptor Agonist

GLP-1R Agonist 14 is a selective agonist for the glucagon-like peptide-1 receptor (GLP-1R), exhibiting an EC50 of 0-20 nM for human GLP-1 receptors. This compound stimulates insulin secretion and inhibits glucagon release, making it a valuable tool for studying glucose metabolism and diabetes-related research. Its strong activity at the GLP-1R positions it as an essential reagent for investigating potential therapeutic strategies in metabolic disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	2758666-01-0
Applications	GLP-1 Receptor Agonist
Formula	C₄₅H₄₂F₂N₁₀O₅
Molecular Weight	840.88
SMILES	C[C@H]1C2=C(C(C3=CC=C(C=C3)F)=NN2CCN1C(C4=CN5C=C(C=CC5=C4C6(CC6)C7=NOC(N7)=O)[C@@H]8CCOC(C)(C8)C)=O)N9C=CN(C9=O)C%10=C(C%11=C(N(N=C%11)C)C=C%10)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.