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GLP-1R agonist 18

GLP-1R Agonist

GLP-1R Agonist 18 is a potent agonist for the glucagon-like peptide-1 receptor (GLP-1R), exhibiting an EC50 of 0.044 nM. This compound enhances insulin secretion in response to glucose, making it a valuable tool for research in diabetes and metabolic disorders. Its high affinity for GLP-1R positions it as a significant candidate for investigating therapeutic strategies targeting glucose homeostasis and appetite regulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	2855243-02-4
Applications	GLP-1R Agonist
Formula	C₃₂H₂₅ClF₄N₄O₄
Molecular Weight	641.01
SMILES	FC1=C2C(N([C@H]3C(C)(COC3)C)C(CC4=C(C=C(C5=NC(OCC6=C(C=C(C=C6)Cl)F)=NC=C5)C(F)=C4)F)=N2)=CC(C(O)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.