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GLP-1R agonist 19

GLP-1R Agonist

GLP-1R agonist 19 is a potent and selective agonist of the glucagon-like peptide-1 receptor (GLP-1R). This compound demonstrates excellent plasma stability and liver microsomal stability, making it suitable for in vitro and in vivo studies. Additionally, it exhibits low hERG toxicity, ensuring a reduced risk of off-target effects. Research applications include investigations into glucose homeostasis, metabolic disorders, and potential therapeutics for type 2 diabetes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	2765065-09-4
Applications	GLP-1R Agonist
Formula	C₉₄H₁₃₆FN₂₁O₂₅
Molecular Weight	1979.21
SMILES	NC([C@H](CCCC1=CC(C)=CC(C)=C1)NC([C@H](CC2=CC=C(C3=C(CC)C=C(OCCCCN4N=NC(COCCOCCOCCOCCOCCOCCOCCOCCN)=C4)C=C3)C=C2)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H]([C@H](O)C)NC([C@@](CC5=C(F)C=CC=C5)(C)NC([C@H]([C@@H](C)O)NC(CNC([C@H](CC6=NNN=N6)NC(C(C)(C)C(NCCC7=CN=CN7)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.