Fig. 1 · Structure

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GLP-1R agonist 20

GLP Receptor Agonist

GLP-1R agonist 20 (Compound I-132) is a selective agonist for the glucagon-like peptide-1 receptor (GLP-1R), exhibiting an EC50 value of 0.0162 nM. This compound plays a crucial role in enhancing insulin secretion and promoting glucose homeostasis. It is valuable for research applications focused on metabolic disorders such as type 2 diabetes and obesity.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 3033288-27-3
Applications GLP Receptor Agonist
Formula C31H30Cl2F2N4O5
Molecular Weight 647.50
SMILES
ClC1=CC(Cl)=C(COC2=C(C(F)F)C=C(CCN(CC3=NC4=C(OC)C=C(C(O)=O)C=C4N3C[C@@H]5CCO5)[C@H]6C)C6=N2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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