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GLP-1R agonist 21

GLP Receptor Agonist

GLP-1R agonist 21 is a selective agonist for the glucagon-like peptide-1 receptor (GLP-1R), exhibiting a potent binding affinity with an EC50 of 0.0104 nM. This compound enhances insulin secretion, promotes glucose-dependent insulin release, and plays a critical role in glucose homeostasis. It is primarily utilized in research related to metabolic disorders, diabetes, and obesity, providing valuable insights into therapeutic strategies targeting GLP-1R pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	3033288-30-8
Applications	GLP Receptor Agonist
Formula	C₃₁H₂₉ClF₄N₄O₅
Molecular Weight	649.03
SMILES	ClC1=CC(F)=C(COC2=C(C(F)F)C=C(CCN(CC3=NC4=C(OC)C=C(C(O)=O)C=C4N3C[C@@H]5CCO5)[C@H]6C)C6=N2)C(F)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.