Fig. 1 · Structure

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GLP-1R agonist 22

GLP Receptor Agonist

GLP-1R agonist 22 is a potent agonist of the glucagon-like peptide-1 receptor (GLP-1R), exhibiting an EC50 value of 0.0165 nM. This compound stimulates insulin secretion and enhances glucose homeostasis, making it a valuable tool for research in diabetes and metabolic disorders. Its specific action on GLP-1R allows for exploration of therapeutic applications in obesity and related conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 3033288-34-2
Applications GLP Receptor Agonist
Formula C30H27ClFN5O4
Molecular Weight 576.02
SMILES
ClC1=CC(F)=C(COC2=C(C#N)C=C(CCN(CC3=NC4=CC=C(C(O)=O)C=C4N3C[C@@H]5CCO5)[C@H]6C)C6=N2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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