Fig. 1 · Structure

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GLP-1R agonist 27

GLP-1R Agonist

GLP-1R agonist 27 is a potent agonist of the glucagon-like peptide-1 receptor (GLP-1R), demonstrating significant oral bioactivity. It enhances cyclic adenosine monophosphate (cAMP) accumulation, which is associated with reduced blood glucose levels and decreased food intake. This compound is instrumental in research related to obesity and type 2 diabetes mellitus (T2DM), offering potential insights into therapeutic approaches for metabolic disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 3086417-33-3
Applications GLP-1R Agonist
Formula C32H33N5O4Se
Molecular Weight 630.60
SMILES
OC(C1=CC(N2C[C@@H]3CCO3)=C(N=C2CN4CCC(C5=NC([Se]CC6=C(C=C(C=C6)C#N)OC)=CC=C5)CC4)C=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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