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GLP-1R agonist 29

GLP-1R Agonist

GLP-1R agonist 29 is a potent agonist of the GLP-1 receptor, effectively stimulating cAMP production with an EC50 value of 0.018 nM. This compound demonstrates favorable pharmacokinetic properties, evidenced by a robust body exposure reflected in an AUC0-∞,sc of 77688 ng·h/mL. It serves as a valuable tool for research applications related to metabolic disorders and diabetes, allowing for exploration of GLP-1R signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	3076770-93-6
Applications	GLP-1R Agonist
Formula	C₄₉H₄₈F₂N₁₀O₅
Molecular Weight	894.97
SMILES	CC1=C(F)C(C)=CC(N2C(N3C=CN(C4=CC=C(N(C5CCC5)N=C6)C6=C4F)C3=O)=C7[C@H](C)N(C(C8=CC9=CC(C%10CCOCC%10)=CC=C9N8[C@@]%11(C%12=NOC(N%12)=O)C[C@@H]%11C)=O)CCC7=N2)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.