Fig. 1 · Structure

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GLP-1R agonist 42

GLP Receptor Agonist

GLP-1R agonist 42 is a potent agonist of the glucagon-like peptide-1 receptor (GLP-1R), exhibiting an EC50 of 0.0122 nM. This compound effectively stimulates insulin secretion and modulates glucagon release, making it relevant for diabetes research. Its application in metabolic studies provides insights into glucose homeostasis and potential therapeutic targets for metabolic disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 3033288-23-9
Applications GLP Receptor Agonist
Formula C31H30ClF3N4O5
Molecular Weight 631.04
SMILES
ClC1=CC=C(COC2=C(C(F)F)C=C(CCN(CC3=NC4=C(OC)C=C(C(O)=O)C=C4N3C[C@@H]5CCO5)[C@H]6C)C6=N2)C(F)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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