Fig. 1 · Structure

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GLP-1R agonist 6

GLP-1R Agonist

GLP-1R agonist 6 is a potent agonist of the GLP-1 receptor, exhibiting an EC50 of 0.15 nM for human GLP-1R. This compound demonstrates significant biological activity in promoting insulin secretion and glucose homeostasis, making it a valuable tool for research in diabetes and metabolic disorders. Its efficacy in activating GLP-1R positions it as a key reagent for exploring therapeutic strategies targeting glucose regulation and appetite control.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 2755653-78-0
Applications GLP-1R Agonist
Formula C29H28ClFN4O5S
Molecular Weight 599.07
SMILES
C[C@@]1(C2=C(C=C(C=C2)Cl)F)OC3=CC=CC(N(CC4)CCN4CC5=NC(SC(C(O)=O)=C6)=C6N5C[C@@H]7CCO7)=C3O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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