Fig. 1 · Structure

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GLP-1R agonist 8

GLP-1R Agonist

GLP-1R agonist 8 is a highly potent agonist of the glucagon-like peptide-1 receptor (GLP-1R), exhibiting an EC50 of less than 2 nM. This compound is instrumental in stimulating insulin secretion and regulating glucose homeostasis, making it a valuable tool in diabetes research and therapeutic development. Its efficacy in enhancing GLP-1R activity underscores its potential for studying metabolic diseases and investigating the physiological roles of GLP-1 signaling pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 2736446-82-3
Applications GLP-1R Agonist
Formula C33H32N4O5
Molecular Weight 564.63
SMILES
N#CC(C=C1)=CC=C1[C@@]2([H])OC3=CC=CC(C(CC4)CCN4CC(N(C5=C6)C[C@@H]7CCO7)=NC5=CC=C6C(O)=O)=C3OC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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