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Biological Activity
GLPG-0259 is a small-molecule inhibitor of mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), a kinase enzyme that plays a role in important inflammatory pathways
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.71 mL | 108.57 mL | 217.14 mL |
| 0.5 mM | 4.34 mL | 21.71 mL | 43.43 mL |
| 1 mM | 2.17 mL | 10.86 mL | 21.71 mL |
| 5 mM | 0.43 mL | 2.17 mL | 4.34 mL |
*The above data is based on the productmolecular weight 460.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18357 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 959754-85-9 |
| Formula | C24H28N8O2 |
| M. Wt | 460.54 |
| Purity | >98% |
| Synonyms | GLPG-0259; GLPG 0259; GLPG0259; |
| SMILES | O=C(C1=CC(C2=CN=C(NC3=CC=C(N4CCN(C(C)(C)C)CC4)C=C3)C5=NC=NN52)=CO1)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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