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GLPG3808

PAPD5/PAPD7 Inhibitor

GLPG3808 is a potent inhibitor of PAPD5 and PAPD7, specifically targeting viral replication processes. This compound effectively reduces the expression of hepatitis B core antigen (HBcAg) in HBV-infected cells and lowers hepatitis B surface antigen levels in animal models of HBV infection. GLPG3808 serves as a valuable tool for research focused on hepatitis B virus pathogenesis and potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2346450-55-1
Applications	PAPD5/PAPD7 Inhibitor
Formula	C₂₄H₂₆ClNO₇
Molecular Weight	475.92
SMILES	COCCCOC(C=C1O[C@@H](C2(C)COC2)C(C=C(C(N3C4CC4)=O)C(O)=O)=C3C1=C5)=C5Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.