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Glucocorticoid receptor agonist-1 Ala-Ala-Mal

Catalog No.: A41370
Glucocorticoid Receptor Agonist
Glucocorticoid receptor agonist-1 Ala-Ala-Mal is a potent agonist of the glucocorticoid receptor, playing a critical role in anti-inflammatory and immunosuppressive pathways. This compound can be strategically conjugated with Adalimumab to develop antibody-drug conjugates (ADCs) for targeted therapy applications. Its functionality makes it a valuable reagent for research in chronic inflammatory conditions and autoimmune diseases.
Glucocorticoid receptor agonist-1 Ala-Ala-Mal 2166376-51-6 Glucocorticoid Receptor Agonist
Grouped product items
Size Price Stock Qty
5mg
$245.00
In stock
10mg
$405.00
In stock
25mg
$800.00
In stock
50mg
$1,230.00
In stock
100mg
$1,920.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGlucocorticoid receptor agonist-1 Ala-Ala-Mal is a potent agonist of the glucocorticoid receptor, playing a critical role in anti-inflammatory and immunosuppressive pathways. This compound can be strategically conjugated with Adalimumab to develop antibody-drug conjugates (ADCs) for targeted therapy applications. Its functionality makes it a valuable reagent for research in chronic inflammatory conditions and autoimmune diseases.
Product Information
Catalog NumA41370
FormulaC48H54N4O11
Molecular Weight862.96
CAS Number2166376-51-6
SMILESO=C([C@]([C@@]1([H])C[C@@]2([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(C=C4)C)([H])[C@H]5O)(O[C@@](C(C=C6)=CC=C6CC7=CC(NC([C@H](C)NC([C@H](C)NC(CCN(C8=O)C(C=C8)=O)=O)=O)=O)=CC=C7)([H])O1)[C@]2(C5)C)CO
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Endocrinology-Hormones > Glucocorticoid receptors