Glucocorticoid receptor agonist-6

Catalog No.: A41097
GR Agonist
Glucocorticoid receptor agonist-6 is a specific agonist for the glucocorticoid receptor (GR). It exhibits significant cytotoxic activity, making it an excellent candidate for use as a payload in the synthesis of antibody-drug conjugates (ADCs). This compound supports research in targeted therapy approaches for diseases where GR modulation is beneficial.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGlucocorticoid receptor agonist-6 is a specific agonist for the glucocorticoid receptor (GR). It exhibits significant cytotoxic activity, making it an excellent candidate for use as a payload in the synthesis of antibody-drug conjugates (ADCs). This compound supports research in targeted therapy approaches for diseases where GR modulation is beneficial.
Product Information
Catalog NumA41097
FormulaC34H51F2O8PS
Molecular Weight688.80
CAS Number2117643-80-6
SMILESO=P(O)(O)CCCCCCCCCCSC([C@@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@H](C2)O)([C@@]4(C([C@H](C3)F)=CC(C=C4)=O)C)F)([H])C[C@H]1C)C)OC(CC)=O)=O
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