Fig. 1 · Structure
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Glucosylsphingosine-13C6
Stable Isotope
Glucosylsphingosine-13C6 is a stable isotope-labeled version of glucosylsphingosine, a deacylated form of glucosylceramide primarily associated with neurotoxic effects. It functions as a non-competitive inhibitor of glucocerebrosidase, exhibiting a Ki value of 30 μM. This compound is valuable in research applications focused on Gaucher disease and Krabbe disease, providing insights into the biochemical pathways and mechanisms involved in these lysosomal storage disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 299172-48-8 |
| Applications | Stable Isotope |
| Formula | C1813C6H47NO7 |
| Molecular Weight | 467.59 |
| Synonyms | Glucopsychosine-13C6; Lyso-Gb1-13C6; Lyso-GL1-13C6 |
| SMILES | CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](N)CO[13C@@H]1O[13C@@H]([13C@H]([13C@@H]([13C@H]1O)O)O)[13CH2]O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.