Fig. 1 · Structure
Documents & Downloads
GluN2B receptor modulator-1
iGluR Modulator
GluN2B receptor modulator-1 is a selective negative allosteric modulator of the GluN2B subtype of the NMDA receptor, exhibiting an IC50 value of 31 nM. This compound is valuable for studying synaptic transmission and neurotransmitter signaling pathways in the central nervous system. Its ability to modulate GluN2B receptor activity makes it a useful tool in research involving neurodegenerative diseases and psychiatric disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 2222010-71-9 |
| Applications | iGluR Modulator |
| Formula | C17H15F3N4O2S |
| Molecular Weight | 396.39 |
| SMILES | O=C1N(C)C2=C(N1CC(N3CCC3)=O)C=C(C4=CC=C(C(F)(F)F)S4)C=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.