Fig. 1 · Structure

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GLUT-1-IN-4

GLUT Inhibitor

GLUT-1-IN-4 is a selective inhibitor of the GLUT-1 glucose transporter, acting through a p53 protein-dependent mechanism. This compound demonstrates potent anticancer activity, effectively inhibiting the proliferation of various cancer cell lines with IC50 values in the submicromolar range. GLUT-1-IN-4 induces cell cycle arrest, promotes oxidative stress, and triggers apoptosis, making it a valuable tool for research in cancer metabolism and therapeutic strategies targeting glucose uptake in tumors.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 735-16-0
Applications GLUT Inhibitor
Formula C15H10N2O3
Molecular Weight 266.25
SMILES
O=[N+]([O-])C1=CC=C(/C=C/C2=CC=NC3=CC=CC=C32)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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