Fig. 1 · Structure
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Glutathione arsenoxide
Tumour Inhibitor
Glutathione arsenoxide (GSAO) is an investigational anticancer agent that functions primarily as a tumor metabolism inhibitor by targeting mitochondrial adenine nucleotide translocase (ANT). This compound induces cell cycle arrest and apoptosis in cancer cells, thereby exhibiting significant antitumor activity. Additionally, GSAO serves as a tool for the identification of cell-surface proteins, including protein disulfide isomerase, contributing to its applications in cancer research and cellular biology studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1271726-51-2 |
| Applications | Tumour Inhibitor |
| Formula | C18H25AsN4O9S |
| Molecular Weight | 548.40 |
| Synonyms | GSAO |
| SMILES | O=C(O)CNC([C@H](CSCC(NC1=CC=C([As](O)O)C=C1)=O)NC(CC[C@@H](C(O)=O)N)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.