Fig. 1 · Structure

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Glutathione monoethyl ester

Glutathione Derivative

Glutathione monoethyl ester is a glutathione derivative that serves as a potent antioxidant, primarily targeting oxidative stress pathways. It demonstrates protective effects on motor neuron cells, particularly NSC-34 cells, by mitigating the pathological damage associated with TDP-43 mutations. This compound effectively reduces aggregation formation, enhances nuclear clearance, decreases reactive oxygen species generation, and prevents cell death. It is a valuable tool for research focused on neurodegenerative diseases and oxidative stress-related conditions.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 118421-50-4
Applications Glutathione Derivative
Formula C12H21N3O6S
Molecular Weight 335.38
SMILES
OC(CNC([C@H](CS)NC(CC[C@H](N)C(O)=O)=O)=O)=O.CCO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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