Fig. 1 · Structure
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Glutathione S-transferase
Glutathione S-transferase
Glutathione S-transferase (GST) is a phase II metabolic enzyme that plays a critical role in detoxification processes by catalyzing the conjugation of glutathione to various electrophilic compounds. It exists in three primary superfamilies: cytosolic, mitochondrial, and microsomal. GST exhibits diverse biological activities, including detoxification, thiol transfer, and chaperone functions. Notably, the GSTP1 isoform is overexpressed in numerous malignant tissues, making it an important tumor marker in cancer research and a valuable target for therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 50812-37-8 |
| Applications | Glutathione S-transferase |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.