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Glutathione trisulfide

Neuroprotective Agent

Glutathione trisulfide (GSSSG) serves as a potent neuroprotective agent, exhibiting significant anti-inflammatory properties. It effectively attenuates LPS-induced inflammatory gene expression in retinal pigment epithelial cells, primarily through hyperactivation of ERK signaling pathways, independent of the NRF2/HMOX1 axis. GSSSG is applicable in studies related to neurodegenerative diseases and ischemic spinal cord injury (SCI), making it a valuable tool for researchers exploring neuroprotection mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	32607-79-7
Applications	Neuroprotective Agent
Formula	C₂₀H₃₂N₆O₁₂S₃
Molecular Weight	644.69
Synonyms	GSSSG
SMILES	[C@@H](NC(CC[C@@H](C(O)=O)N)=O)(C(NCC(O)=O)=O)CSSSC[C@H](NC(CC[C@@H](C(O)=O)N)=O)C(NCC(O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.