Documents & Downloads

GLX481372

NOX Inhibitor

GLX481372 is a NADPH Oxidase (NOX) inhibitor that selectively targets NOX4 and NOX5 with IC50 values of 0.68 and 0.57 μM, respectively. It demonstrates weaker inhibitory effects on NOX1, NOX2, and NOX3, with IC50 values of 7, 16, and 3.2 μM. By inhibiting reactive oxygen species (ROS) production, GLX481372 serves as a valuable tool in research pertaining to inflammation, cardiovascular diseases, and metabolic disorders, including diabetes.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1990478-58-4
Applications	NOX Inhibitor
Formula	C₂₃H₂₉N₇
Molecular Weight	403.52
SMILES	CC1=CC(NC2=NC(N)=NC(CN3CCN(CC3)C4=CC=C(C)C=C4)=N2)=CC=C1C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.