Fig. 1 · Structure
Documents & Downloads
Glycerol dioleate
Sustained-release Component
Glycerol dioleate is a lipid that serves as a sustained-release component through the formation of Lyotropic Liquid Crystals (LLC). When combined with phosphatidylcholine in aqueous media, it generates an inverted hexagonal (HII) phase structure conducive to prolonged release. This gel system, optimized with N-methyl-2-pyrrolidone, allows for stable release of Risperidone for up to 60 days in both in vitro and in vivo settings. Glycerol dioleate is associated with minimal side effects in animal models, positioning it as an effective carrier for the delivery of antipsychotic agents.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 25637-84-7 |
| Applications | Sustained-release Component |
| Formula | C39H72O5 |
| Molecular Weight | 621.00 |
| SMILES | CCCCCCCC/C=C\CCCCCCCC(OC(COC(CCCCCCC/C=C\CCCCCCCC)=O)CO)=O.CCCCCCCC/C=C\CCCCCCCC(OCC(COC(CCCCCCC/C=C\CCCCCCCC)=O)O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.