Glycol chitosan is a water-soluble polymer derived from chitosan, featuring ethylene glycol branches that enhance membrane permeability. This compound exhibits significant antimicrobial activity, inhibiting the growth of E. coli, S. aureus, and S. enteritidis with minimum inhibitory concentrations (MIC) of 4 μg/mL, 32 μg/mL, and <0.5 μg/mL, respectively. Due to its biocompatibility and biodegradability, glycol chitosan is an excellent candidate for various biomedical applications, including drug delivery systems and tissue engineering.
Fig. 1 · Structure
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Glycol chitosan
Water-Soluble Polymer
Glycol chitosan is a water-soluble polymer derived from chitosan, featuring ethylene glycol branches that enhance membrane permeability. This compound exhibits significant antimicrobial activity, inhibiting the growth of E. coli, S. aureus, and S. enteritidis with minimum inhibitory concentrations (MIC) of 4 μg/mL, 32 μg/mL, and <0.5 μg/mL, respectively. Due to its biocompatibility and biodegradability, glycol chitosan is an excellent candidate for various biomedical applications, including drug delivery systems and tissue engineering.
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Biological Activity
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 123938-86-3 |
| Applications | Water-Soluble Polymer |
| Molecular Weight | 82685.58 |
| SMILES | N[C@@H]1[C@@H](O)[C@H](O)[C@@H](COCCO)O[C@H]1O[C@@H]2[C@@H](COCCO)O[C@@H](O[C@@H]3[C@@H](COCCO)O[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)[C@H]2O.[n] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.