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Glycolate oxidase-IN-1

Glycolate Oxidase Inhibitor

Glycolate oxidase-IN-1 is a potent inhibitor of glycolate oxidase, demonstrating an IC50 of 38.2 μM. This salicylic acid derivative effectively reduces oxalate production in hyperoxalate hepatocytes, making it a valuable tool for investigating primary hyperoxaluria type 1 (PH1). Its application in research provides insights into metabolic disorders related to oxalate metabolism.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	330977-65-6
Applications	Glycolate Oxidase Inhibitor
Formula	C₁₂H₈O₅
Molecular Weight	232.19
SMILES	O=C(O)C1=CC(C2=CC=C(C=O)O2)=CC=C1O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.