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Glycyl-Exatecan

DE-310 Active Metabolite

Glycyl-Exatecan is the active metabolite of DE-310, produced through enzymatic cleavage of its spacer. This compound demonstrates significant anti-tumor activity in vivo, making it a valuable tool for oncology research. Glycyl-Exatecan is particularly applicable in studies focusing on solid tumors.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	849479-60-3
Applications	DE-310 Active Metabolite
Formula	C₂₆H₂₅FN₄O₅
Molecular Weight	492.50
Synonyms	Glycyl-DX-8951; Exatecan analog 2
SMILES	NCC(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.