Fig. 1 · Structure

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GMQ hydrochloride

ASIC Activator

GMQ hydrochloride is an ASIC (acid-sensing ion channel) activator specifically targeting ASIC3, with an EC50 value of 1.83 mM at pH 7.4. This compound selectively activates ASIC3 without influencing other ASIC subtypes at physiological pH. GMQ hydrochloride is valuable for research applications focused on neurological diseases, facilitating the exploration of ASIC3's role in neuronal activity and related pathologies.

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Specifications

Manufacturer Adooq Bioscience
Actions Activator
CAS Number 5361-15-9
Applications ASIC Activator
Formula C10H12ClN5
Molecular Weight 237.69
Synonyms 2-Guanidine-4-methylquinazoline hydrochloride
SMILES
CC1=NC(NC(N)=N)=NC2=CC=CC=C12.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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