GNE-4997

Catalog No.: A17188

ITK inhibitor

GNE-4997

GNE-4997 Chemical Structure

CAS NO. 1705602-02-3

GNE-4997 is a potent and selective ITK inhibitor with Ki value of 0.09 nM.

Availability: In stock

Package Price Qty
5 mg
$450.00
10 mg
$820.00
50 mg
$3,200.00
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Biological Activity

GNE-4997 is a potent and selective ITK inhibitor with Ki value of 0.09 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.41 mL 97.05 mL 194.11 mL
0.5 mM 3.88 mL 19.41 mL 38.82 mL
1 mM 1.94 mL 9.71 mL 19.41 mL
5 mM 0.39 mL 1.94 mL 3.88 mL

*The above data is based on the productmolecular weight 515.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17188
Actions Inhibitor
CAS No. 1705602-02-3
Formula C25H27F2N5O3S
M. Wt 515.18
Solubility DMSO
Purity >98%
Synonyms GNE4997, GNE 4997
SMILES O=C(C1=NNC2=C1C[[email protected]](C(F)3F)[[email protected]@]3(C)C2)NC4=CN(N=C4)[[email protected]](C5=CC=CC=C5)[[email protected]@H]6S(CCCC6)(=O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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