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Catalog No.: A13748

LRRK2 inhibitor


GNE-7915 Chemical Structure

CAS NO. 1351761-44-8

GNE-7915 is a Blood-Brain Barrier (BBB) penetrable small molecule inhibitor of Leucine-Rich Repeat Kinase 2 (LRRK2).

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10 mg

Regular Price: $90.00

Special Price $72.00

25 mg

Regular Price: $180.00

Special Price $144.00

50 mg

Regular Price: $300.00

Special Price $240.00

100 mg

Regular Price: $470.00

Special Price $376.00

10mM * 1mL in DMSO

Regular Price: $100.00

Special Price $80.00

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Biological Activity

GNE-7915 is a Blood-Brain Barrier (BBB) penetrable small molecule inhibitor of Leucine-Rich Repeat Kinase 2 (LRRK2).
1 nM(Ki)9 nM
In vitro (25°C) DMSO Warmed: 21 mg/mL (47.36 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+30% PEG 300+5% Tween 80+ddH2O 2.9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.55 mL 112.77 mL 225.53 mL
0.5 mM 4.51 mL 22.55 mL 45.11 mL
1 mM 2.26 mL 11.28 mL 22.55 mL
5 mM 0.45 mL 2.26 mL 4.51 mL

*The above data is based on the productmolecular weight 443.395. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13748
Actions Inhibitor
CAS No. 1351761-44-8
Formula C19H21F4N5O3
M. Wt 443.395
Purity >98%
Synonyms GNE7915, GMS 7915

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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