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LRRK2 inhibitor

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Catalog No. A13748

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GNE-7915 10mg A13748-10

Regular Price: €85.50

Special Price: €76.95

GNE-7915 25mg A13748-25

Regular Price: €171.00

Special Price: €153.90

GNE-7915 50mg A13748-50

Regular Price: €285.00

Special Price: €256.50

GNE-7915 100mg A13748-100

Regular Price: €446.50

Special Price: €401.85

GNE-7915 10mM * 1mL in DMSO A13748-10mM-D

Regular Price: €95.00

Special Price: €85.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GNE-7915 is a Blood-Brain Barrier (BBB) penetrable small molecule inhibitor of Leucine-Rich Repeat Kinase 2 (LRRK2).


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Chemical Information

Catalog Num A13748
Actions Inhibitor
M. Wt ?443.39535
Formula C19H21F4N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1351761-44-8
Synonyms GNE7915, GMS 7915

Biological Activity

GNE-7915 is a Blood-Brain Barrier (BBB) penetrable small molecule inhibitor of Leucine-Rich Repeat Kinase 2 (LRRK2).
1 nM(Ki)9 nM


Solubility (25°C)* In vitro DMSO 22 mg/mL heating (49.61 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 0 mL 0 mL 0mL
0.5 mM 0 mL 0 mL 0 mL
1 mM 0 mL 0 mL 0 mL
5 mM 0 mL 0 mL 0 mL

*The above data is based on the productmolecular weight ?443.39535. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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