GNE-7915

Catalog No.: A13748

LRRK2 inhibitor

GNE-7915 Chemical Structure

CAS NO. 1351761-44-8

GNE-7915 is a Blood-Brain Barrier (BBB) penetrable small molecule inhibitor of Leucine-Rich Repeat Kinase 2 (LRRK2).

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$180.00
50 mg
$300.00
100 mg
$470.00
10mM * 1mL in DMSO
$100.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

GNE-7915 is a Blood-Brain Barrier (BBB) penetrable small molecule inhibitor of Leucine-Rich Repeat Kinase 2 (LRRK2).
Targets
LRRK2 LRRK2
1 nM(Ki)9 nM
In vitro DMSO 22 mg/mL heating (49.61 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Catalog Num A13748
Actions Inhibitor
M. Wt ?443.39535
Formula C19H21F4N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1351761-44-8
Synonyms GNE7915, GMS 7915
SMILES CCNC1=NC(=NC=C1C(F)(F)F)NC2=C(C=C(C(=C2)F)C(=O)N3CCOCC3)OC

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