GNE-7915
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | GNE-7915 is a Blood-Brain Barrier (BBB) penetrable small molecule inhibitor of Leucine-Rich Repeat Kinase 2 (LRRK2). | ||
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Targets |
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Catalog Num | A13748 |
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Formula | C19H21F4N5O3 |
Molecular Weight | 443.395 |
CAS Number | 1351761-44-8 |
SMILES | CCNC1=NC(=NC=C1C(F)(F)F)NC2=C(C=C(C(=C2)F)C(=O)N3CCOCC3)OC |
Synonyms | GNE7915, GMS 7915 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 21 mg/mL (47.36 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+30% PEG 300+5% Tween 80+ddH2O | 2.9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.55 mL | 112.77 mL | 225.53 mL |
0.5 mM | 4.51 mL | 22.55 mL | 45.11 mL |
1 mM | 2.26 mL | 11.28 mL | 22.55 mL |
5 mM | 0.45 mL | 2.26 mL | 4.51 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2