GNE-9822 is a potent and selective inhibitor of ITK (Interleukin-2-inducible T-cell kinase) with a Ki value of 0.7 nM and an EC50 value of 354.5 nM. This compound demonstrates favorable ADME properties, making it suitable for in vivo studies. GNE-9822 is primarily utilized in research on asthma and other related immunological conditions, providing insights into the modulation of T-cell signaling pathways.
GNE-9822 is a potent and selective inhibitor of ITK (Interleukin-2-inducible T-cell kinase) with a Ki value of 0.7 nM and an EC50 value of 354.5 nM. This compound demonstrates favorable ADME properties, making it suitable for in vivo studies. GNE-9822 is primarily utilized in research on asthma and other related immunological conditions, providing insights into the modulation of T-cell signaling pathways.
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