GNE7599 is a high-affinity von Hippel-Lindau (VHL) ligand, characterized by a dissociation constant (Kd) of 540 pM. This compound serves as a crucial component for the development of Proteolysis Targeting Chimeras (PROTACs), facilitating the targeted degradation of specific proteins. Its ability to bind with high specificity to VHL makes it an invaluable tool for research in targeted protein modulation and therapeutic applications in cancer and other diseases.
GNE7599 is a high-affinity von Hippel-Lindau (VHL) ligand, characterized by a dissociation constant (Kd) of 540 pM. This compound serves as a crucial component for the development of Proteolysis Targeting Chimeras (PROTACs), facilitating the targeted degradation of specific proteins. Its ability to bind with high specificity to VHL makes it an invaluable tool for research in targeted protein modulation and therapeutic applications in cancer and other diseases.
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