Fig. 1 · Structure
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GNF7686
Cytochrome b Inhibitor
GNF7686 is a selective inhibitor of cytochrome b, specifically targeting complex III in mitochondrial respiration. This compound demonstrates significant inhibitory activity against the parasites Leishmania donovani and Trypanosoma cruzi, making it valuable for research on diseases such as leishmaniasis and Chagas disease. Its effective modulation of complex III provides insights into the metabolic pathways of these protozoan infections and aids in the development of potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 442567-43-3 |
| Applications | Cytochrome b Inhibitor |
| Formula | C15H13N3O |
| Molecular Weight | 251.28 |
| SMILES | N#CC1=C(C)C(CC)=C(O)N2C3=C(C=CC=C3)N=C12 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.