Fig. 1 · Structure
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GNX-865
mPTP Inhibitor
GNX-865 is an inhibitor of the mitochondrial permeability transition pore (mPTP) that plays a crucial role in cellular protection against ischemia-reperfusion injury. This compound has demonstrated effectiveness in mitigating cell death and promoting cell survival in various in vivo models. Its applications extend to research focused on cardiovascular diseases and mitochondrial dysfunction, making it a valuable tool for studying therapeutic strategies in ischemic conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1223568-82-8 |
| Applications | mPTP Inhibitor |
| Formula | C16H14ClNO3 |
| Molecular Weight | 303.74 |
| SMILES | O=C(/C=C/C1=CC=C(C(O)=C1)OC)NC2=CC=CC(Cl)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.