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PKC inhibitor

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Catalog No. A13790

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
GO6983 10mg A13790-10
GO6983 25mg A13790-25
GO6983 50mg A13790-50
GO6983 10mM * 1mL in DMSO A13790-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

GO6983 is a potent protein kinase C (PKC) inhibitor. It reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.


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Chemical Information

Catalog Num A13790
Actions Inhibitor
M. Wt 442.51
Formula C26H26N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 133053-19-7
Synonyms Go-6983, Go 6983

Biological Activity

GO6983 is a potent protein kinase C (PKC) inhibitor. It reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.
Target Value
PKCγIC50: 6nM
PKCαIC50: 7nM
PKCβIC50: 7nM
PKCδIC50: 10nM
PKCζIC50: 60nM
PKCμIC50: 20μM


Solubility (25°C) * In vitro DMSO 59 mg/mL (133.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.6 mL 112.99 mL 225.98mL
0.5 mM 4.52 mL 22.6 mL 45.2 mL
1 mM 2.26 mL 11.3 mL 22.6 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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