Golexanolone

Catalog No.: A66933
GABAA Receptor Antagonist
Golexanolone is a GABAA receptor antagonist that modulates steroid activity. This compound demonstrates significant effects on reducing peripheral inflammation and neuroinflammation, contributing to enhanced cognitive and motor functions in hyperammonemic rat models. Golexanolone serves as a valuable tool for investigating the mechanisms underlying neurological disorders and peripheral inflammation.
Grouped product items
Size Price Stock Qty
1mg
$235.00
In stock
5mg
$590.00
In stock
10mg
$830.00
In stock
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGolexanolone is a GABAA receptor antagonist that modulates steroid activity. This compound demonstrates significant effects on reducing peripheral inflammation and neuroinflammation, contributing to enhanced cognitive and motor functions in hyperammonemic rat models. Golexanolone serves as a valuable tool for investigating the mechanisms underlying neurological disorders and peripheral inflammation.
Product Information
Catalog NumA66933
FormulaC21H31NO2
Molecular Weight329.48
CAS Number2089238-18-4
SMILESC[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@@](O)(CC2)C#C)([H])[C@@]4([H])[C@](CC3)(/C(CC4)=N/O)C
SynonymsGR3027
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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