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Goxalapladib

Catalog No.: A29408
5-HT6 Receptor Modulator/Lp-PLA2 Inhibitor
Goxalapladib is a selective modulator of the 5-HT6 receptor that also serves as an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Its mechanism of action suggests potential applications in the investigation of atherosclerosis-related cardiovascular diseases. This compound facilitates research into the modulation of lipid metabolism and inflammation, making it a valuable tool for studies focused on cardiovascular health.
Goxalapladib 412950-27-7 5-HT6 Receptor Modulator/Lp-PLA2 Inhibitor
Grouped product items
Size Price Stock Qty
1mg
$95.00
In stock
5mg
$240.00
In stock
10mg
$350.00
In stock
25mg
$545.00
In stock
50mg
$730.00
In stock
100mg
$945.00
In stock
200mg
$1,265.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGoxalapladib is a selective modulator of the 5-HT6 receptor that also serves as an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Its mechanism of action suggests potential applications in the investigation of atherosclerosis-related cardiovascular diseases. This compound facilitates research into the modulation of lipid metabolism and inflammation, making it a valuable tool for studies focused on cardiovascular health.
Product Information
Catalog NumA29408
FormulaC40H39F5N4O3
Molecular Weight718.75
CAS Number412950-27-7
SMILESO=C1C=C(CCC2=C(F)C(F)=CC=C2)N(CC(N(C3CCN(CC3)CCOC)CC4=CC=C(C5=CC=C(C(F)(F)F)C=C5)C=C4)=O)C6=NC=CC=C16
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > 5-HT Receptors