Fig. 1 · Structure
Documents & Downloads
GP3269
Adenosine Kinase Inhibitor
GP3269 is a selective and orally active inhibitor of human adenosine kinase (AK), exhibiting an IC50 of 11 nM. This compound effectively elevates adenosine levels at epileptic foci and activates A1 receptors on excitatory neurons, demonstrating anticonvulsant activity in rodent models. GP3269 is particularly useful for research focused on epilepsy and related neurological disorders, as it does not induce adverse hemodynamic effects such as alterations in blood pressure or heart rate.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 186393-42-0 |
| Applications | Adenosine Kinase Inhibitor |
| Formula | C23H21FN4O3 |
| Molecular Weight | 420.44 |
| SMILES | O[C@H]([C@@H]([C@H](O1)C)O)[C@]1([H])N2C3=NC=NC(NC4=CC=C(C=C4)F)=C3C(C5=CC=CC=C5)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.