Fig. 1 · Structure
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GPVI antagonist 2
GPVI Antagonist
GPVI Antagonist 2 targets Glycoprotein VI (GPVI), a major collagen receptor on platelets. It exhibits effective antagonistic activity with IC50 values of 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin, and 81.38 μM for thrombin. This compound is of particular interest for antithrombotic research, as it holds promise as a potent and safe antiplatelet agent for cardiovascular studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 880399-00-8 |
| Applications | GPVI Antagonist |
| Formula | C24H27N3O4 |
| Molecular Weight | 421.49 |
| SMILES | O=C1N(CCCO)C(C2=CC=CC(OCCCC)=C2)C3=C1NN=C3C4=CC=CC=C4O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.