GR 250495X

Catalog No.: A64762
Glucocorticoid Receptor Agonist
GR 250495X is a glucocorticoid receptor agonist designed for localized action in the lungs. As an antedrug, it undergoes rapid metabolism and inactivation in the bloodstream, reducing systemic side effects. This reagent is particularly valuable in asthma research, providing insights into therapeutic mechanisms and efficacy in pulmonary conditions.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGR 250495X is a glucocorticoid receptor agonist designed for localized action in the lungs. As an antedrug, it undergoes rapid metabolism and inactivation in the bloodstream, reducing systemic side effects. This reagent is particularly valuable in asthma research, providing insights into therapeutic mechanisms and efficacy in pulmonary conditions.
Product Information
Catalog NumA64762
FormulaC28H36F2O7S
Molecular Weight554.64
CAS Number192057-17-3
SMILESO=C(OCC1)[C@H]1SC([C@]23[C@@]4([C@@]([C@@]5([H])[C@]([C@H](C4)O)([C@@]6(C([C@H](C5)F)=CC(CC6)=O)C)F)([H])C[C@@]2([H])O[C@H](O3)CCC)C)=O
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