GR65630

Catalog No.: A29729
5-HT Type 3 Receptor Antagonist
GR65630 acts as a potent and selective antagonist of the 5-hydroxytryptamine (5-HT) type 3 receptor. This compound is valuable for investigating the expression patterns of 5-HT3 receptors across various brain regions and elucidating their roles within the central nervous system. Additionally, GR65630, along with its radiolabeled form [3H]GR65630, can be employed to analyze receptor distribution, density, and binding affinity, facilitating advancements in neuropharmacological research.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionGR65630 acts as a potent and selective antagonist of the 5-hydroxytryptamine (5-HT) type 3 receptor. This compound is valuable for investigating the expression patterns of 5-HT3 receptors across various brain regions and elucidating their roles within the central nervous system. Additionally, GR65630, along with its radiolabeled form [3H]GR65630, can be employed to analyze receptor distribution, density, and binding affinity, facilitating advancements in neuropharmacological research.
Product Information
Catalog NumA29729
FormulaC16H17N3O
Molecular Weight267.33
CAS Number113140-33-3
SMILESO=C(CCC1=C(C)N=CN1)C2=CN(C)C3=C2C=CC=C3
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