Fig. 1 · Structure
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GRP78-IN-2
GRP78 Inhibitor
GRP78-IN-2 is a selective inhibitor of GRP78 (Glucose Regulated Protein 78 kDa), primarily targeting its cell surface form. This compound demonstrates significant antiangiogenic and anticancer properties, effectively inhibiting tumor growth while sparing normal cells. GRP78-IN-2 is a valuable tool for researchers studying tumor biology and potential therapeutic strategies in cancer treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1882875-63-9 |
| Applications | GRP78 Inhibitor |
| Formula | C29H29NO6 |
| Molecular Weight | 487.54 |
| SMILES | COC1=CC(OC)=CC(C(OCC2=CC=C(C=C2)C3=C(C4=CC=CC=C4O3)C(NCC(C)C)=O)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.