Fig. 1 · Structure
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GS-704277
Remdesivir Metabolite
GS-704277 is an alanine metabolite of Remdesivir that undergoes further hydrolysis to form GA-441524, known for its antiviral properties. This compound plays a crucial role in antiviral research, particularly in studying the mitigation of SARS-CoV-2 (COVID-19) infection. Its significance lies in its ability to function as a key intermediate in the metabolic pathway of Remdesivir, supporting investigations into viral replication inhibition and therapeutic efficacy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1911579-04-8 |
| Applications | Remdesivir Metabolite |
| Formula | C15H19N6O8P |
| Molecular Weight | 442.32 |
| SMILES | OC([C@H](C)NP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@@](C2=CC=C3N2N=CN=C3N)(C#N)O1)(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.