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Biological Activity
GS-9901 is a highly selective and orally active PI3Kδ inhibitor, with an IC50 of 1 nM. Has potential to treat rheumatoid arthritis.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.93 mL | 104.63 mL | 209.26 mL |
| 0.5 mM | 4.19 mL | 20.93 mL | 41.85 mL |
| 1 mM | 2.09 mL | 10.46 mL | 20.93 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.19 mL |
*The above data is based on the productmolecular weight 477.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12988 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1640247-87-5 |
| Formula | C22H17ClFN9O |
| M. Wt | 477.88 |
| Purity | >98% |
| Synonyms | GS9901, GS 9901 |
| SMILES | NC1=NC(N)=NC(N[[email protected]](C2CC2)C(N3C4=CN=CC=C4)=NC5=C(F)C=CC(Cl)=C5C3=O)=C1C#N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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